Publikationen IZKS

Originalarbeiten (Zeitschriften) im Jahr 2019

  1. Klimas , Gorfinkel , Giacomuzzi , Ruckes , Socias , Fairbairn , Wood . Slow release oral morphine versus methadone for the treatment of opioid use disorder. BMJ OPEN 2019; 9: Im Druck
  2. Wölfling K, Müller KW, Dreier M, Ruckes C, Deuster O, Batra A, Mann K, Musalek M, Schuster A, Lemenager T, Hanke S, Beutel ME. Efficacy of Short-term Treatment of Internet and Computer Game Addiction: A Randomized Clinical Trial. JAMA Psychiatry 2019; : Im Druck
  3. Schulz M, Griese-Mammen N, Anker SD, Koehler F, Ihle P, Ruckes C, Schumacher PM, Trenk D, Böhm M, Laufs U. Pharmacy-based interdisciplinary Intervention for patients with chronic heart failure: results of the PHARM-CHF randomized controlled trial. Eur J Heart Fail 2019; 21: 1012-1021
  4. Moehler M, Maderer A, Ehrlich A, Foerster F, Schad A, Nickolay T, Ruckes C, Weinmann A, Sivanathan V, Marquardt JU, Galle PR, Woerns M, Thomaidis T. Safety and efficacy of afatinib as add-on to Standard therapy of gemcitabine/Cisplatin in chemotherpay-naive patients with advanced biliary tract Cancer: open-label, phase I Trial with an extensive biomarker program. BMC Cancer 2019; 19: Im Druck
  5. Aggensteiner PM, Brandels D, Millenet S, Hohmann S, Ruckes C, Beuth S, Albrecht B, Schmitt G, Schermuly S, Wörz S, Gevensleben H, Freitag CM, Banaschewski T, Rothenberger A, Strehl U, Holtmann M. Slow cortical potentials neurofeedback in Children with ADHD: comorbidity, self-regulation and clinical Outcomes 6 months after Treatment in a multicenter randomized controlled trial. Eur Child Adolesc Psych 2019; 28: 1087-1095

Originalarbeiten (Zeitschriften) im Jahr 2018

  1. Huber Y, Boyle M, Hallsworth K, Tiniakos D, Straub BK, Labenz C, Ruckes C, Galle PR, Romero-Gómez M, Anstee QM, Schattenberg JM, EPoS Consortium Investigators . Health-related Quality of Life in Non-alcoholic Fatty Liver Disease Associates With Hepatic Inflammation. Clin Gastroenterol Hepatol 2018; : Im Druck
  2. Holtmann M, Mokros L, Kirschbaum-Lesch I, Kölch M, Plener PL, Ruckes C, Schulte-Markwort M, Legenbauer T. Adolescent depression: Study protocol for a randomized, controlled, double-blind multicenter parallel group trial of Bright Light Therapy in a naturalistic inpatient Setting (DeLight). Trials 2018; 19: 568
  3. Labenz C, Huber Y, Kalliga E, Nagel M, Ruckes C, Straub BK, Galle PR, Wörns MA, Anstee QM, Schuppan D, Schattenberg JM. Predictors of advanced fibrosis in non-cirrhotic non-alcoholic fatty liver disease in Germany. Aliment Pharmacol Ther 2018; 48: 1109-1116
  4. Mulfinger N, Müller S, Böge I, Sakar V, Corrigan PW, Evans-Lacko S, Nehf L, Djamali J, Samarelli A, Kempter M, Ruckes C, Libal G, Oexle N, Noterdaeme M, Rüsch N. Honest, Open, Proud for adolescents with mental illness: pilot randomized controlled trial. J Child Psychol Psychiatry 2018; 59: 684-691
  5. Ballmann M, Hubert D, Assael BM, Staab D, Hebestreit A, Naehrlich L, Nickolay T, Prinz N, Holl RW, CFRD Study Group . Repaglinide versus Insulin for newly diagnosed Diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised Trial. Lancet Diabetes Endocrinol 2018; 6: 114-121
  6. Kanniess F, Ruckes C, Regenfuß N, Schmidt T. GERDA (GERman Dmp Asthma) - GERNOD (GERmaN cOpd Dmp): Does efficacy of DMP COPD depend on disease severity?. Dtsch Med Wochenschr 2018; 143: 1-9
  7. Hess G, Hüttmann A, Meissner J, Marks R, Dreyling M, Keller U, Ernst T, Pott C, Viardot A, Deuster O, van Oordt C, Theobald M, Lenz L. Obinutuzumab (GA101) in Combination with Pixantrone for the Treatment of Patients with Relapsed Aggressive B-Cell Lymphoma: A Phase II Trial (GOAL)‏ . Blood 2018; 132: 1678-1678
  8. Hess G, Hüttmann A, Meissner M, Marks R, Dreyling M, Keller U, Ernst T, Pott C, Viardot A, Deuster O, Theobald M, Lenz G. Obinutuzumab (GA101) in combination with Pixantrone for the treatment of patients with relapsed Aggressive B-cell Lymphoma: Interim report of a phase II trial: GOAL. Blood 2018; : Im Druck
  9. Deuster O. EMCL-Register. 2018; : Im Druck

Originalarbeiten (Zeitschriften) im Jahr 2017

  1. Wiltink J, Ruckes C, Hoyer J, Leichsenring F, Joraschky P, Leweke F, Pöhlmann K, Beutel ME. Transfer of manualized Short Term Psychodynamic Psychotherapy (STPP) for social anxiety disorder into clinical practice: results from a cluster-randomised controlled trial . BMC Psychiatry 2017; 17: Im Druck
  2. Herzog DP, Wagner S, Ruckes C, Tadic A, Roll SC, Härtner M, Lieb K. Guideline adherence of antidepressant treatment in outpatients with major depressive disorder: a naturalistic study. Eur Arch Psychiatry Clin Neurosci 2017; 267: 711-721
  3. Franke AG, Gränsmark P, Agricola P, Schühle K, Rommel T, Sebastian A, Balló HE, Gorbulev S, Gerdes C, Frank B, Ruckes C, Tüscher O, Lieb K. Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial. Eur Neuropsychopharmacol 2017; 27: 248-260
  4. Lorenz K, Wasielica-Poslednik J, Bell K, Renieri G, Keicher A, Ruckes C, Pfeiffer N, Thieme H. Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. PLoS One 2017; 15: Im Druck
  5. Strehl U, Aggensteiner P, Wachtlin D, Brandeis D, Albrecht B, Arana M, Bach C, Banaschewski T, Flaig-Röhr A, Freitag CM, Fuchsenberger Y, Gest S, Gevensleben H, Herde L, Legenbauer T, Marx AM, Millenet S, Pniewski B, Rothenberger A, Ruckes C, Wörz S, Holtmann M. Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects. Front Hum Neurosci 2017; : Im Druck
  6. Jaithe LES, Helwig SA, Jaqne A, Ragoschke-Schumm A, Sarr C, Walter S, Lesmeister M, Manitz M, Blaß D, Weis S, Schlund V, Bah N, Kauffmann J, Fousse M, Kangankan S, Ramos Cabrera A, Kronfeld K, Ruckes C, Liu Y, Nyan O, Fassbender K. Standard operating procedures improve acute neurologic care in a sub-Saharan African Setting. Neurology 2017; 89: 144-152
  7. Kahaly GJ, Riedl M, König J, Diana T, Schomburg L. Double-Blind, Placebo-Controlled, Randomized Trial of Selenium in Graves Hyperthyroidism. J Clin Endocrinol Metab 2017; 102: 4333-4341
  8. Meyer , Gortner L, NeoVitaA Trial investigators . Up-date on the NeoVitaA Trial: Obstacles, challenges, perspectives, and local experiences. Wien Med Wochenschr 2017; 167: 264-270

Originalarbeiten (Zeitschriften) im Jahr 2016

  1. Wiltink J, Hoyer J, Beutel ME, Ruckes C, Herpertz S, Joraschky P, Koranyi S, Michal M, Nolting B, Pöhlmann K, Salzer S, Strauss B, Leibing E, Leichsenring F. Do patient characteristics predict outcome of psychodynamic psychotherapy for social anxiety disorder?. PLoS ONE 2016; 11: e0147165
  2. Ferner M, Wachtlin D, Konrad T, Deuster O, Meinertz T, von Bardeleben S, Münzel T, Seibert-Grafe M, Breithardt G, Rostock T. Rationale and design of the RE-LATED AF-AFNET 7 trial: REsolution of Left atrial-Appendage Thrombus-Effects of Dabigatran in patients with Atrial Fibrillation. Clin Res Cardiol 2016; 105: 29-36
  3. Tadić A, Wachtlin D, Berger M, Braus DF, van Calker D, Dahmen N, Dreimüller N, Engel A, Gorbulev S, Helmreich I, Kaiser AK, Kronfeld K, Schlicht KF, Tüscher O, Wagner S, Hiemke C, Lieb K. Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression - the EMC trial. Eur Neuropsychopharmacol 2016; 26: 705-16
  4. Kauff DW, Kronfeld K, Gorbulev S, Wachtlin D, Lang H, Kneist W. Continuous intraoperative monitoring of pelvic autonomic nerves during TME to prevent urogenital and anorectal dysfunction in rectal cancer patients (NEUROS): a randomized controlled trial. BMC Cancer 2016; 16: 323
  5. Riedl M, Kuhn A, Krämer I, Kolbe E, Kahaly GJ. Prospective, systematically recorded mycophenolate safety data in Graves' orbitopathy. J Endocrinol Invest 2016; 39: 687-94
  6. Moehler M, Gepfner-Tuma I, Maderer A, Thuss-Patience PC, Ruessel J, Hegewisch-Becker S, Wilke H, Al-Batran SE, Rafiyan MR, Weißinger F, Schmoll HJ, Kullmann F, von Weikersthal LF, Siveke JT, Weusmann J, Kanzler S, Schimanski CC, Otte M, Schollenberger L, Koenig J, Galle PR. Sunitinib added to FOLFIRI versus FOLFIRI in patients with chemorefractory advanced adenocarcinoma of the stomach or lower esophagus: a randomized, placebo-controlled phase II AIO trial with serum biomarker program. BMC Cancer 2016; 16: 699
  7. Zahn D, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller W, Kronfeld K, Kruse J, Kulzer B, Müller MJ, Ruckes C, Petrak F. hs-CRP Predicts Improvement in Depression in Patients With Type 1 Diabetes and Major Depression Undergoing Depression Treatment: Results From the Diabetes and Depression (DAD) Study. Diabetes Care 2016; 39: 171-173

Originalarbeiten (Zeitschriften) im Jahr 2015

  1. Pitton MB, Kloeckner R, Ruckes C, Wirth GM, Eichhorn W, Wörns MA, Weinmann A, Schreckenberger M, Galle PR, Otto G, Dueber C. Randomized comparison of selective internal radiotherapy (SIRT) versus drug-eluting bead transarterial chemoembolization (DEB-TACE) for the treatment of hepatocellular carcinoma. Cardiovasc Intervent Radiol 2015; 38: 352-60
  2. Hess G, Keller U, Scholz CW, Witzens-Harig M, Atta J, Buske C, Kirschey S, Ruckes C, Medler C, van Oordt C, Klapper W, Theobald M, Dreyling M. Safety and efficacy of temsirolimus in combination with bendamustine and rituximab in relapsed mantle cell and follicular lymphoma. Leukemia 2015; 29: 1695-701
  3. Werhahn KJ, Trinka E, Dobesberger J, Unterberger I, Baum P, Deckert-Schmitz M, Kniess T, Schmitz B, Bernedo V, Ruckes C, Ehrlich A, Krämer G. A randomized, double-blind comparison of antiepileptic drug treatment in the elderly with new-onset focal epilepsy. Epilepsia 2015; 56: 450-9
  4. Petrak F, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller W, Kronfeld K, Kruse J, Kulzer B, Ruckes C, Zahn D, Müller MJ. Cognitive behavioral therapy versus sertraline in patients with depression and poorly controlled diabetes: the diabetes and depression (DAD) study: a randomized controlled multicenter trial. Diabetes Care 2015; 38: 767-75
  5. Kloeckner R, Weinmann A, Prinz F, Pinto dos Santos D, Ruckes C, Dueber C, Pitton MB. Conventional transarterial chemoembolization versus drug-eluting bead transarterial chemoembolization for the treatment of hepatocellular carcinoma. BMC Cancer 2015; 15: 465
  6. Adrian M, Wachtlin D, Kronfeld K, Sommerfeldt D, Wessel LM. A comparison of intervention and conservative treatment for angulated fractures of the distal forearm in children (AFIC): study protocol for a randomized controlled trial. Trials 2015; 16: 437
  7. Sprinzl MF, Grambihler A, Kittner JM, Wachtlin D, Ruckes C, Schattenberg J, Ehrlich A, Alshuth U, Wörns M, Schuchmann M, Galle PR. Prospective randomized open-label trial protocol investigating the addition of pegylated interferon-alpha to an ongoing nucleos(t)ide treatment regimen of HBeAg negative chronic hepatitis B patients (PADD-ON). J Clin Trials 2015; 5: 226
  8. Hess G, Keller U, Atta J, Bitz U, Lerchenmueller C, Wagner K, Medler C, Ruckes C, Witzens-Harig M, Huebel K, LaRosee P, Dreyling MH. Temsirolimus in combination with bendamustine and rituximab for the treatment of relapsed mantle cell and follicular lymphoma: report on an ongoing phase I/II trial. BLOOD 2015; 126: 3930
  9. Riedl M, Kolbe E, Kampmann E, Krämer I, Kahaly GJ. Prospectively recorded and MedDRA-coded safety data of intravenous methylprednisolone therapy in Graves' orbitopathy. J Endocrinol Invest 2015; 38: 177-82

Originalarbeiten (Zeitschriften) im Jahr 2014

  1. Moehler M, Maderer A, Schimanski C, Kanzler S, Denzer U, Kolligs FT, Ebert MP, Distelrath A, Geissler M, Trojan J, Schütz M, Berie L, Sauvigny C, Lammert F, Lohse A, Dollinger MM, Lindig U, Duerr EM, Lubomierski N, Zimmermann S, Wachtlin D, Kaiser AK, Schadmand-Fischer S, Galle PR, Woerns M, . Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme. Eur J Cancer 2014; 50: 3125-35
  2. Holtmann M, Pniewski B, Wachtlin D, Wörz S, Strehl U. Neurofeedback in children with attention-deficit/hyperactivity disorder (ADHD)--a controlled multicenter study of a non-pharmacological treatment approach. BMC Pediatr 2014; 14: 202
  3. Kloeckner R, Ruckes C, Kronfeld K, Wörns MA, Weinmann A, Galle PR, Lang H, Otto G, Eichhorn W, Schreckenberger M, Dueber C, Pitton MB. Selective internal radiotherapy (SIRT) versus transarterial chemoembolization (TACE) for the treatment of intrahepatic cholangiocellular carcinoma (CCC): study protocol for a randomized controlled trial. Trials 2014; 15: 311
  4. Hämmig R, Köhler W, Bonorden-Kleij K, Weber B, Lebentrau K, Berthel T, Babic-Hohnjec L, Vollmert C, Höpner D, Gholami N, Verthein U, Haasen C, Reimer J, Ruckes C. Safety and tolerability of slow-release oral morphine versus methadone in the treatment of opioid dependence. J Subst Abuse Treat 2014; 47: 275-81
  5. Schnorbus B, Daiber A, Jurk K, Warnke S, König J, Krahn U, Lackner K, Munzel T, Gori T. Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patients undergoing coronary artery stenting for an acute coronary syndrome. A randomised, prospective, contro. BMJ Open 2014; 4: e005268
  6. Witt JA, Werhahn KJ, Krämer G, Ruckes C, Trinka E, Helmstaedter C. Cognitive-behavioral screening in elderly patients with new-onset epilepsy before treatment. Acta Neurol Scand 2014; 130: 172-7
  7. Ballmann M, Hubert D, Assael BM, Kronfeld K, Honer M, Holl RW, . Open randomised prospective comparative multi-centre intervention study of patients with cystic fibrosis and early diagnosed diabetes mellitus. BMC Pediatr 2014; 14: 70
  8. Nusselt T, Hofmann A, Wachtlin D, Gorbulev S, Rommens PM. CERAMENT treatment of fracture defects (CERTiFy): protocol for a prospective, multicenter, randomized study investigating the use of CERAMENT™ BONE VOID FILLER in tibial plateau fractures. Trials 2014; 15: 75
  9. Beutel ME, Weißflog G, Leuteritz K, Wiltink J, Haselbacher A, Ruckes C, Kuhnt S, Barthel Y, Imruck BH, Zwerenz R, Brähler E. Efficacy of short-term psychodynamic psychotherapy (STPP) with depressed breast cancer patients: results of a randomized controlled multicenter trial. Ann Oncol 2014; 25: 378-84
  10. Beck T, Haasen C, Verthein U, Walcher S, Schuler C, Backmund M, Ruckes C, Reimer J. Maintenance treatment for opioid dependence with slow-release oral morphine: a randomized cross-over, non-inferiority study versus methadone. Addiction 2014; 109: 617-26
  11. Foltys D, Zimmermann T, Kaths M, Strempel M, Heise M, Hoppe-Lotichius M, Weiler N, Scheuermann U, Ruckes C, Hansen T, Pitton M, Otto G. Hepatocellular carcinoma in Child's A cirrhosis: a retrospective analysis of matched pairs following liver transplantation vs. liver resection according to the intention-to-treat principle. Clin Transplant 2014; 28: 37-46

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